| 产品编号 | D50916 |
| 英文名称 | Furamidine dihydrochloride |
| 中文名称 | |
| 别 名 | PRMT1抑制剂 |
| 克 隆 号 | |
| CAS | 55368-40-6 |
| 理论分子量 | 377.27 kDa |
| 检测分子量 | |
| 性 状 | Lyophilized |
| 保存条件 | Store in dry, dark place for one year. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
Furamidine is a potent, selective and cell permeable Protein arginine methyltransferase-1 (PRMT1) inhibitor with IC50 of 9.4 μM. It has >10-fold selectivity PRMT5, PRMT6 and CARM1 (IC50 are 166, 283 and >400 μM respectively). It targets the enzyme active site and is primarily competitive with the substrate and noncompetitive toward the cofactor. Furamidine effectively inhibits intracellular PRMT1 activity and blocks cell proliferation in leukemia cell lines with different genetic lesions. |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
