| 产品编号 | D50887 |
| 英文名称 | RG2833 (RGFP109) |
| 中文名称 | |
| 别 名 | Brain-penetrant HDAC抑制剂 |
| 克 隆 号 | |
| CAS | 1215493-56-3 |
| 理论分子量 | 339.43 kDa |
| 检测分子量 | |
| 性 状 | Lyophilized |
| 保存条件 | Store in dry, dark place for one year. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
RG2833 (RGFP109) is a potent and selective brain-penetrant HDAC inhibitor with IC50 of 60 nM and 50 nM for HDAC1 and HDAC3, respectively. It upregulates frataxin mRNA and protein levels dose-dependently in cultures of unstimulated peripheral blood mononuclear cells (PBMC) obtained from FRDA patients. In vivo it corrects frataxin deficiency and increases histone acetylation in the brain and heart of KIKI mice without acute toxicity signs. |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
