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Methoxy-X04 (D50805)  
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2mg/380.00元
10mg/1280.00元
大包装/询价
产品编号 D50805
英文名称 Methoxy-X04
中文名称
别    名   β淀粉样蛋白荧光探针
克 隆 号
CAS 863918-78-9
理论分子量 344.4 kDa
检测分子量
性    状 Lyophilized
保存条件 Store in dry, dark place for one year.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Methoxy-X04 is a fluorescent amyloid β (Aβ) probe for the detection and quantification of plaques, tangles and cerebrovascular amyloid with good specificity. It is a derivative of Congo red and Chrysamine-G that contains no acid groups and is therefore smaller and much more lipophilic than Congo red or Chrysamine-G. Methoxy-X04 retains in vitro binding affinity for amyloid beta (Abeta) fibrils (Ki = 26.8 nM) very similar to that of Chrysamine-G. Using multiphoton microscopy to obtain high-resolution (1 microm) fluorescent images from the brains of living PSI/APP mice, individual plaques could be distinguished within 30 to 60 min after a single IV injection or a single IP injection of Methoxy-X04.

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