| 产品编号 | D50799 |
| 英文名称 | C646 |
| 中文名称 | |
| 别 名 | p300/CBP抑制剂 |
| 克 隆 号 | |
| CAS | 328968-36-1 |
| 理论分子量 | 445.42 kDa |
| 检测分子量 | |
| 性 状 | Lyophilized |
| 保存条件 | Store in dry, dark place for one year. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
C646 is a potent, selective and cell-permeable p300/CBP histone acetyltransferase (HAT) inhibitor with an IC50 ~400 nM. It competes with acetyl-CoA for the p300 Lys-CoA binding pocket selectively. It blocks the growth of human melanoma, leukemia, lung, and prostate cancer cells in vitro. C646 has also been used to study the role of p300-mediated gene regulation in neuroscience. The histone acetyltransferase (HAT) p300/CBP is a transcriptional coactivator implicated in many gene regulatory pathways and protein acetylation events. C646 is a useful chemical probe to study p300/CBP HAT functions. |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
