| 产品介绍 |
Rapamycin is a potent and selective mTOR inhibitor. Rapamycin, in complex with the cytosolic protein FK-binding protein 12 (FKBP12), inhibits mTOR Complex 1 (mTORC1) by binding to the FRB domain of mTor. Given the central roles mTor plays, Rapamycin showed diverse activities, including anti-proliferative effects in cancer cells, immunosuppressive effect, lifespan extension in mice, improved cognition in the mouse model of autism and Alzheimer, and inducing autophagy.
基本信息：
CAS：53123-88-9
分子式：C51H79NO13
分子量：914.18
MDL：MFCD00867594
纯度：≥98%
外观/性状：类白色固体
熔点：183-185°C
沸点：973.017 °C at 760 mmHg
溶解性：溶于DMSO, 甲醇，极微溶于水。
敏感性：对热敏感
产品简介：
雷帕霉素 (Rapamycin) 是大环内酯类抗生素。是一种有效且特异性的 mTOR 抑制剂，作用于 HEK293 细胞，抑制 mTOR，IC50 为 0.1 nM。Rapamycin 与
|
