| 产品编号 | D50720 |
| 英文名称 | DAPT |
| 中文名称 | |
| 别 名 | γ-secretase抑制剂 |
| 克 隆 号 | |
| CAS | 208255-80-5 |
| 理论分子量 | 432.46 kDa |
| 检测分子量 | |
| 性 状 | Lyophilized |
| 保存条件 | Store in dry, dark place for one year. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
DAPT is a widely used γ-secretase inhibitor and serves as an inhibitor of Notch, a γ-secretase substrate. It can also cause a reduction in Aβ40 and Aβ42 levels in human primary neuronal cells (IC50 ~115 nM for total Aβ and ~200 nM for Aβ42) and in brain extracts, as well as in vivo. Since the Notch pathway is involved in development of many cell types, DAPT is used to modulate Notch activity in ESC/iPSC or adult stem cell differentiation studies. |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
