| 产品编号 | D50710 |
| 英文名称 | XAV939 |
| 中文名称 | |
| 别 名 | Wnt拮抗剂 |
| 克 隆 号 | |
| CAS | 284028-89-3 |
| 理论分子量 | 312.31 kDa |
| 检测分子量 | |
| 性 状 | Lyophilized |
| 保存条件 | Store in dry, dark place for one year. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
XAV939 is a potent and selective Wnt pathway antagonist. It functions to stabilize Axin by inhibiting the poly-ADP-ribosylating enzymes tankyrase 1 and tankyrase 2 with IC50 of 11 nM and 4 nM, respectively. It has been used to study Wnt-dependent cancers. In addition, XAV939 was shown to stabilize Axin2 level in oligodendrocyte precursor cells in the spinal cord and accelerated their differentiation and myelination after hypoxic and demyelinating injury. It can also robustly induce cardiomyocyte differentiation from mouse and human ESCs/iPSCs. |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
