产品编号 | D50707 |
英文名称 | RO4929097 |
中文名称 | |
别 名 | γ-Secretase抑制剂 |
克 隆 号 | |
CAS | 847925-91-1 |
理论分子量 | 469.4 kDa |
检测分子量 | |
性 状 | Lyophilized |
保存条件 | Store in dry, dark place for one year. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 |
RO4929097 is a highly potent and selective γ-secretase inhibitor with an IC50 ~4 nM. It can cause a dramatic reduction of the intracellular Notch level and lead to significantly decreased expression of the Notch transcriptional target genes, such as Hes1. It exhibits potent inhibitory activity of Notch signaling in tumor cells. Currently RO4929097 is in multiple phase I/II clinical trials to treat cancer. |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |