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beta-Amyloid(1-42) Mouse mAb, PE conjugated (V5304-PE)  
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100ul/2980.00元
大包装/询价
产品编号 V5304-PE
英文名称 beta-Amyloid(1-42) Mouse mAb, PE conjugated
中文名称 PE标记的β淀粉样肽(1-42)单克隆抗体
别    名 beta-Amyloid(1-42); A4; AAA; ABETA; ABPP; AD1; Alzheimers Disease Amyloid Protein; Amyloid B; Amyloid Beta A4 Protein Precursor; Amyloid Beta; Amyloid of Aging and Alzheimer Disease; APP; APPI; B Amyloid; Beta APP; Cerebral Vascular Amyloid Peptide; CTFgamma; CVAP; PN II; PN2; PreA4; Protease nexin II; A beta; Amyloid 1-42; Aβ1-42.  
克 隆 号 3D12
理论分子量 kDa
检测分子量
缓 冲 液 0.01M PBS(pH7.4).
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
产品介绍 The cerebral and vascular plaques associated with Alzheimer's disease are mainly composed of Amyloid beta peptides. beta Amyloid is derived from cleavage of the Amyloid precursor protein and varies in length from 39 to 43 amino acids. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides result from cleavage of Amyloid precursor protein after residues 40, 42, and 43, respectively. The cleavage takes place by gamma-secretase during the last Amyloid precursor protein processing step. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides are major constituents of the plaques and tangles that occur in Alzheimer's disease. beta Amyloid antibodies and peptides have been developed as tools for elucidating the biology of Alzheimer's disease.

SWISS:
P05067

Gene ID:
351

β-Amyloid 也称βA4 蛋白,是β-淀粉样蛋白前体(APP)经β和γ分泌酶分解后的产物,有39-43个氨基酸残基组成。是淀粉样蛋白的主要成分。 β-淀粉样蛋白来自β-淀粉样蛋白原,在脑组织的细胞外呈丝状蛋白样沉积 ,是淀粉样结节性神经炎病变的主要蛋白成分,在神经纤维中也有沉积。
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