产品编号 | bs-43655P |
英文名称 | Recombinant human Coagulation factor II protein/F2, C-His (HEK293) |
中文名称 | 重组人异常凝血酶原蛋白 |
别 名 | Des-gamma-carboxy (abnormal)prothrombin; Des-Gamma-carboxy-prothrombin; coagulation factor II (thrombin); DCP; Factor II; Prepro coagulation factor II; Prothrombin; prothrombin B-chain; PT; RPRGL2; serine protease; THPH1; THRB; THRB_HUMAN; Thrombin heavy chain. |
理论分子量 | 31.8kDa |
性 状 | Lyophilized or Liquid |
浓 度 | >0.5mg/ml |
物 种 | Human |
序 列 | 44-413/622 |
纯 度 | >90% as determined by SDS-PAGE |
纯化方法 | AC |
内毒素 | Not analyzed |
表达系统 | HEK293 cell |
标签 | C-His |
缓 冲 液 | PBS (pH=7.4). |
保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 |
Des-gamma carboxyprothrombin (DCP), also known as protein induced by vitamin K absence/antagonist-II (PIVKA-II), is an abnormal form of the coagulation protein, prothrombin. Normally, the prothrombin precursor undergoes post-translational carboxylation (addition of a carboxylic acid group) by gamma-glutamyl carboxylase in the liver prior to secretion into plasma. DCP/PIVKA-II may be detected in people with deficiency of vitamin K (due to poor nutrition or malabsorption) and in those taking warfarin or other medication that inhibits the action of vitamin K. SWISS: P00734 Gene ID: 2147 正常肝细胞中,在内质网内可将DCP羧化使之成为有活性的凝血酶原,一旦机体需要,凝血酶原即可转变成凝血酶参与机体的各项生理功能,当有肿瘤细胞发生时,DCP明显升高。DCP主要用于肝癌方面的研究;有学者认为:联合应用DCP和AFP对于早期诊断HCC(原发性肝细胞癌)有较大的帮助。 |
产品图片 | |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |