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Human PGI (V4102)
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说明书: 定制/大包装  
定制/大包装/询价
大包装/询价
产品编号 V4102
英文名称 Human PGI
中文名称 人胃蛋白酶原单克隆抗体
别    名 Pepsin A-4; PEPA4_HUMAN; PGA4; pepsinogen 4, group I (pepsinogen A); Pepsin A 4; Pepsinogen-4  
克 隆 号 6B7
理论分子量 42kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
缓 冲 液 0.01M PBS(pH7.4)
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity (pH 1-3) for pepsin function. Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids. Pepsin shows extremely broad specificity, and although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. The amino acid composition of Pepsin C differs from those of pepsinogen and pepsin especially in the content of basic amino acids, glutamic acid, aspartic acid, leucine and isoleucine.

Function:
Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent.

Subcellular Location:
Secreted.

Similarity:
Belongs to the peptidase A1 family.

SWISS:
P0DJD7

Gene ID:
643847

Database links:

Entrez Gene: 643847 Human


SwissProt: P0DJD7 Human



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