产品编号 |
bs-42083P |
英文名称 |
Recombinant mouse DMBT1 protein, C-His
|
中文名称 |
重组小鼠抑癌基因蛋白 |
别 名 |
GP340; Apactin; CRP; CRP-[a]; CRP-[b]; CRP-ductin; Crpd; DBMT1; Deleted in malignant brain tumors 1; Deleted in malignant brain tumors 1 protein; DMBT 1; DMBT1 prototype precursor; DMBT1/6kb.1 protein precursor; DMBT1/8kb.1 protein; DMBT1/8kb.2 protein pr |
理论分子量 |
23.1 kDa |
检测分子量 |
|
性 状 |
Lyophilized or Liquid |
浓 度 |
>1mg/ml |
物 种 |
Mouse |
纯 度 |
>90% as determined by SDS-PAGE |
纯化方法 |
AC |
内毒素 |
Not analyzed |
表达系统 |
E.coli |
标签 |
C-His |
缓 冲 液 |
20mM Tris-HCl (pH8.0) with 8M Urea & 5mM DTT. |
保存条件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 |
DMBT 1 may play roles in mucosal defense system, cellular immune defense and epithelial differentiation. May play a role in liver regeneration. May be an important factor in fate decision and differentiation of transit-amplifying ductular(oval) cells within the hepatic lineage. May function as a binding protein in saliva for the regulation of taste sensation. May play a role as an opsonin receptor for SFTPD and SPAR in macrophages tissues throughout the body, including epithelial cells lining the gastrointestinal tract. Required for terminal differentiation of columnar epithelial cells during early embryogenesis. [Subcellular Location] Secreted. Membrane. [Tissue Specificity] Expressed in von Ebner glands (VEG) (at protein level), olfactory epithelium and the lateral nasal gland. Expressed in transit-amplifying ductular (oval) cells. Up-regulated at day 3 after hepatectomy. Expressed in newly formed bile ducts and in structures resembling intestinal epithelium. Belongs to the DMBT1 family.
DMBT1是分泌型的清道夫受体,富含半胱氨酸,主要在肠道表达,参与再生和防御病原体的功能。 有学者认为:DMBT1在消化系统的恶性肿瘤的发生、发展及转移中起一定作用。
|
产品图片 |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
|
|
|