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产品中心-北京博奥森生物技术有限公司
Recombinant mouse ABCA12 protein, N-His (bs-42207P)  
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100ug/2980.00元
500ug/9500.00元
大包装/询价

产品编号 bs-42207P
英文名称 Recombinant mouse ABCA12 protein, N-His
中文名称 重组小鼠腺苷三磷酸结合盒转运体12蛋白
别    名 ABC transporter A family member 12; ABC transporter ABCA.12; ABC12; ABCA12; ABCAC_HUMAN; AtABCA12; ATH16; ATP binding cassette 12; ATP binding cassette sub family A (ABC1) member 12; ATP binding cassette sub family A member 12; ATP binding cassette transp  
理论分子量 26.1 kDa
检测分子量
性    状 Lyophilized or Liquid
浓    度 >0.5mg/ml
物    种 Mouse
纯    度 >90% as determined by SDS-PAGE
纯化方法 AC
内毒素 Not analyzed
表达系统 E.coli
标签 N-His
缓 冲 液 20mM Tris-HCl (pH7.4) with 8M Urea.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 The ATP-binding cassette (ABC) transporters, or traffic ATPases, constitute an expansive family of proteins accountable for the transport of a wide variety of substrates across cell membranes in both prokaryotic and eukaryotic cells. They also aid in the regulation of lipid transport and membrane trafficking. ABCA12 (ATP-Binding Cassette, Subfamily A, Member 12) contains two transmembrane (TM) domains, each with six membrane-spanning segments, and two nucleotide-binding domains (NBDs), which are located in the cytoplasm. ABCA12 is expressed in normal human keratinocytes (RT-PCR reveals expression in placenta, testis, fetal brain, and skin) and is upregulated during keratinization. Immunoelectron microscopy reveals that the ABCA12 protein is located in lamellar granules in the upper epidermal keratinocytes of human skin. The ABCA12 gene, which synthesizes a 2,595-amino acid protein, may produce an alternative splice variant with an in-frame deletion leading to truncation of 79 amino acids.

Gene ID:
74591

产品图片
The purity of the protein is greater than 85% as determined by reducing SDS-PAGE.
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