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产品中心-北京博奥森生物技术有限公司
Recombinant human CD86 protein, C-His (HEK293) (bs-43589P)  
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产品编号 bs-43589P
英文名称 Recombinant human CD86 protein, C-His (HEK293)
中文名称 重组人CD86蛋白
别    名 CD28LG2; FUN1; LAB72; Activation B7 2 antigen; Activation B7-2 antigen 3; CD86_HUMAN; Activation B7-2 antigen; Activation B72 antigen; B lymphocyte activation antigen B7 2; B lymphocyte activation antigen B72; B-lymphocyte activation antigen B7-2 2; B-lym  
理论分子量 25.7 kDa
检测分子量
性    状 Lyophilized or Liquid
浓    度 >0.5mg/ml
物    种 Human
纯    度 >90% as determined by SDS-PAGE
纯化方法 AC
内毒素 Not analyzed
表达系统 HEK293 cell
标签 C-His
缓 冲 液 PBS (pH7.4).
保存条件 Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011].

SWISS:
P42081

Gene ID:
942

CD86是一个很重要要的辅助刺激分子,CD86作为CD28的辅助刺激分子,提供 T 细胞活化的辅助信号,它们之间的结合和随后介导的信号转导是 T 细胞和 APC 相互协作的重要分子基础。
产品图片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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