| 产品编号 | bs-42218P |
| 英文名称 | Recombinant human LPL protein, N-His |
| 中文名称 | 重组人脂蛋白脂酶 |
| 别 名 | Lipoprotein lipase; LIPD; LIPL_HUMAN; LPL; LPL protein; EC 3.1.1; EC 3.1.1.34; HDLCQ11; LPL; LPL protein; MGC137861. |
| 理论分子量 | 26.2 kDa |
| 检测分子量 | |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | ＞1.0 mg/ml |
| 物 种 | Human |
| 纯 度 | >90% as determined by SDS-PAGE |
| 纯化方法 | AC |
| 内毒素 | Not analyzed |
| 表达系统 | E.coli |
| 标签 | N-His |
| 缓 冲 液 | 20mM Tris-HCl (pH8.0) with 8M Urea. |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
Lipoprotein lipase (LPL) is the central enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space. Evidence has been provided that LPL produced by macrophages in the vessel wall exerts proatherogenic effects. The atherogenic effects of LPL have been mainly attributed to its ability to favor lipid accumulation within macrophages present in the atherosclerotic lesion. Recently, it has also been shown that LPL promote the development of atherosclerosis through facilitation of monocyte adhesion to endothelial cells, stimulation of tumor necrosis factor alpha (TNF ) secretion and induction of vascular smooth muscle cell proliferation. SWISS: P06858 Gene ID: 4023 脂蛋白脂酶（lipoprteinlipase，LPL）是甘油三酯降解为甘油和游离脂肪酸 (FFA)反应的限速酶,是脂肪细胞、心肌细胞、骨骼肌细胞、乳腺细胞以及巨噬细胞等实质细胞合成和分泌的一种糖蛋白与机体的脂质代谢及肥胖与否密切相关. 近年来研究认为：LPL可通过粘附作用，促进了单核细胞血管内皮细胞及肿瘤坏死因子（TNF）的分泌、血管平滑肌细胞增殖等因素，导致动脉粥样硬化的加重。 |
| 产品图片 |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
|
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
