产品编号 | bs-34232R |
英文名称 | Rabbit Anti-ROR1 antibody |
中文名称 | 非酪氨酸蛋白激酶跨膜受体ROR1抗体 |
别 名 | ROR1_HUMAN; ROR1_MOUSE; Inactive tyrosine-protein kinase transmembrane receptor ROR1; Neurotrophic tyrosine kinase, receptor-related 1; NTRKR1; receptor tyrosine kinase like orphan receptor 1; dJ537F10.1; |
研究领域 | 染色质和核信号 神经生物学 信号转导 激酶和磷酸酶 细胞分化 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | (predicted: Human,Mouse) |
产品应用 | WB=1:300-800
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 100kDa |
细胞定位 | 细胞膜 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from mouse ROR1 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | PBS with 0.02% Proclin300, 100μg/ml BSA and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 |
This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012] Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Expressed strongly in human heart, lung and kidney, but weakly in the CNS. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm. SWISS: Q9Z139 Gene ID: 26563 |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |