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Rabbit Anti-Clusterin  antibody (bsm-60757R)  
~~~促销代码KT202411~~~
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说明书: 50ul  100ul  
50ul/1580.00元
100ul/2500.00元
大包装/询价
产品编号 bsm-60757R
英文名称 Rabbit Anti-Clusterin  antibody
中文名称 载脂蛋白J(APOJ)重组兔单抗
别    名 CLUS_HUMAN; Aging-associated gene 4 protein; Apolipoprotein J (Apo-J); Complement cytolysis inhibitor (CLI); Complement-associated protein SP-40,40; Ku70-binding protein 1; NA1/NA2; Sulfated glycoprotein 2 (SGP-2); Testosterone-repressed prostate message 2 (TRPM-2); APOJ; CLI; KUB1; AAG4; CLU2; SGP2; SP-40; TRPM2; CLU;  
研究领域 肿瘤  心血管  细胞生物  免疫学  脂蛋白  
抗体来源 Rabbit
克隆类型 Recombinant
交叉反应 (predicted: Mouse,Rat)
产品应用 WB=1:500-1000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
细胞定位 分泌型蛋白 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CLU 
亚    型 IgG/Kappa
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants.[provided by RefSeq, May 2011]

Subcellular Location:
Nucleus. Cytoplasm. Mitochondrion membrane. Cytoplasm, cytosol. Microsome. Endoplasmic reticulum. Cytoplasmic vesicle, secretory vesicle, chromaffin granule. Isoforms lacking the N-terminal signal sequence have been shown to be cytoplasmic and/or nuclear. Secreted isoforms can retrotranslocate from the secretory compartments to the cytosol upon cellular stress. Detected in perinuclear foci that may be aggresomes containing misfolded, ubiquitinated proteins. Detected at the mitochondrion membrane upon induction of apoptosis and Secreted. Can retrotranslocate from the secretory compartments to the cytosol upon cellular stress.

Tissue Specificity:
Detected in blood plasma, cerebrospinal fluid, milk, seminal plasma and colon mucosa. Detected in the germinal center of colon lymphoid nodules and in colon parasympathetic ganglia of the Auerbach plexus (at protein level). Ubiquitous. Detected in brain, testis, ovary, liver and pancreas, and at lower levels in kidney, heart, spleen and lung.

SWISS:
P10909

Gene ID:
1191

Database links:



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