| 产品编号 |
bs-42139P |
| 英文名称 |
Recombinant human GBP2 protein, N-His
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| 中文名称 |
重组G蛋白结合蛋白2 |
| 别 名 |
GBP 2; GBP2; GBP-2; GTP binding protein 2; Guanine nucleotide binding protein 2; Guanylate binding protein 2 interferon inducible; HuGBP 2; HuGBP2; GBP2_HUMAN. |
| 克 隆 号 |
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| 理论分子量 |
31.2 kDa |
| 性 状 |
Lyophilized or Liquid |
| 浓 度 |
>1mg/ml |
| 物 种 |
Human |
| 序 列 |
50-306/591 |
| 纯 度 |
>90% as determined by SDS-PAGE |
| 纯化方法 |
AC |
| 内毒素 |
Not analyzed |
| 表达系统 |
E.coli |
| 活性 |
Not tested |
| 标签 |
N-His |
| 缓 冲 液 |
20mM Tris (pH8.0) with 8M Urea. |
| 保存条件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
Guanylate-binding proteins, GBP1 and GBP2 are GTP-binding proteins with a high-turnover GTPase activity and an antiviral effect (1-4). GBP1 mediates an antiviral effect against vesicular stomatitis virus and encephalomyocarditis virus and plays a role in the IFN-mediated antiviral response against these viruses (4). GBP1 and GBP2 belong to a group of large GTP-binding proteins with a high concentration-dependent GTPase activity that have the common ability to undergo oligomerization (1). GBP1 and GBP2 are bone marrow-derived GTPases encoded by interferon-activated genes and are inducible following IFN treatment (2,3). Specifically, GBP1 is expressed in cultured mammary epithelial tumor cell lines after treatment with IFN-gamma and LPS (5).
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| 产品图片 |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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