| 产品编号 | bsm-60742M |
| 英文名称 | HDAC3 |
| 中文名称 | 组蛋白去乙酰化酶3单克隆抗体 |
| 别 名 | RPD3 2; RPD3-2; HD 3; HD3; HDAC 3; Histone deacetylase 3 (HD3) (RPD3-2); histone deacetylase 3; RPD 3; RPD3; SMAP 45; SMAP-45; SMAP45; HDAC3_HUMAN |
| 研究领域 | 肿瘤 细胞生物 发育生物学 转录调节因子 表观遗传学 |
| 抗体来源 | Mouse |
| 克隆类型 | Recombinant |
| 交叉反应 | (predicted: Human,Mouse,Rat) |
| 产品应用 | WB=1:500, IHC-P=1:100-500, ICC=1:50, IF=1:50
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 47kDa |
| 细胞定位 | 细胞核 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human HDAC3 |
| 亚 型 | IgG2b, Kappa |
| 纯化方法 | affinity purified by Protein G |
| 缓 冲 液 | PBS, Glycerol, BSA |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008]. SWISS: O15379 Gene ID: 8841 Database links: Entrez Gene: 8841 Human Entrez Gene: 15183 Mouse Omim: 605166 Human SwissProt: O15379 Human SwissProt: O88895 Mouse Unigene: 519632 Human Unigene: 20521 Mouse Unigene: 17284 Rat
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
