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beta-Amyloid (1-42) Mouse mAb (V5305)  
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大包装/询价
产品编号 V5305
英文名称 beta-Amyloid (1-42) Mouse mAb
中文名称 β淀粉样肽(1-42)单克隆抗体
别    名 beta-Amyloid(1-42); A4; AAA; ABETA; ABPP; AD1; Alzheimers Disease Amyloid Protein; Amyloid B; Amyloid Beta A4 Protein Precursor; Amyloid Beta; Amyloid of Aging and Alzheimer Disease; APP; APPI; B Amyloid; Beta APP; Cerebral Vascular Amyloid Peptide; CTFga  
克 隆 号 1F9
理论分子量 4.4 kDa
检测分子量
细胞定位 细胞核 细胞浆 细胞膜 细胞外基质 
性    状 Liquid
纯    度 >90% as determined by SDS-PAGE
缓 冲 液 0.01M PBS (pH7.4).
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 The cerebral and vascular plaques associated with Alzheimer's disease are mainly composed of Amyloid beta peptides. beta Amyloid is derived from cleavage of the Amyloid precursor protein and varies in length from 39 to 43 amino acids. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides result from cleavage of Amyloid precursor protein after residues 40, 42, and 43, respectively. The cleavage takes place by gamma-secretase during the last Amyloid precursor protein processing step. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides are major constituents of the plaques and tangles that occur in Alzheimer's disease. beta Amyloid antibodies and peptides have been developed as tools for elucidating the biology of Alzheimer's disease.

SWISS:
P05067

Gene ID:
351

Database links:

Entrez Gene: 351 Human

Entrez Gene: 11820 Mouse

Entrez Gene: 54226 Rat

Omim: 104760 Human

SwissProt: P05067 Human

SwissProt: P12023 Mouse

SwissProt: P08592 Rat

Unigene: 434980 Human

Unigene: 277585 Mouse

Unigene: 2104 Rat




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