| 产品编号 | bsm-30220M-PE |
| 英文名称 | Mouse Anti-human CD284 (TLR4)/PE antibody |
| 中文名称 | PE标记人CD284 (TLR4)单克隆抗体 |
| 别 名 | TLR-4; TLR 4; ARMD10; CD 284; CD284; CD284 antigen; Homolog of Drosophila toll; hTol; Toll (Drosophila) homolog; TOLL; Toll Endotoxin Hyporesponsiveness; Toll like receptor 4; Toll like receptor 4 precursor; TLR4_HUMAN. |
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Specific References (1) | bsm-30220M-PE has been referenced in 1 publications.
[IF=6.429] Ying Jun. et al. Aspirin increases chemosensitivity of colorectal cancer cells and inhibits the expression of toll-like receptor 4. CANCER CELL INT. 2023 Dec;23(1):1-9 FCM ; Human,Mouse.
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| 抗体来源 | Mouse |
| 克隆类型 | Monoclonal |
| 克 隆 号 | 3D4 |
| 交叉反应 | |
| 产品应用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 90kDa |
| 检测分子量 | 110 |
| 性 状 | Liquid |
| 亚 型 | Mouse IgG2a, κ |
| 纯化方法 | Affinity purified by Protein G |
| 缓 冲 液 | 0.01M PBS, 0.5%BSA, 0.03% Proclin300 |
| 保存条件 | Store at 2-8℃. Protect from light. Avoid freezing. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. In silico studies have found a particularly strong binding of surface TLR4 with the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of Coronavirus disease-2019 (COVID-19). This receptor has also been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness, and with susceptibility to age-related macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2020] SWISS: O00206 Gene ID: 7099 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
