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phospho-V-Myb+C-Myb (Ser11) Recombinant Rabbit mAb (bsm-54494R)  
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50ul/1400.00元
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大包装/询价
产品编号 bsm-54494R
英文名称 phospho-V-Myb+C-Myb (Ser11) Recombinant Rabbit mAb
中文名称 磷酸化转录激活因子MYB重组兔单抗
别    名 Avian myeloblastosis viral(v-myb) oncogene homolog; C myb; c-Myb; MYB_HUMAN; Proto-oncogene c-Myb; Transcriptional activator Myb; v-myb avian myeloblastosis viral oncogene homolog.  
产品类型 磷酸化抗体 重组兔单抗 
研究领域 肿瘤  免疫学  染色质和核信号  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Recombinant
克 隆 号
交叉反应 Human
产品应用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:50-200,ICC/IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 84 kDa
检测分子量
细胞定位 细胞核 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human MYB around the phosphorylation site of Ser11 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.

Function:
Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.

Subcellular Location:
Nucleus.

Post-translational modifications:
Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation.
Phosphorylated by NLK on multiple sites, which induces proteasomal degradation.

Similarity:
Contains 3 HTH myb-type DNA-binding domains.

SWISS:
P10242

Gene ID:
4602

Database links:

Entrez Gene: 4602 Human

Entrez Gene: 17863 Mouse

Entrez Gene: 498982 Rat

SwissProt: P46200 Cow

SwissProt: P10242 Human

SwissProt: P06876 Mouse



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