产品编号 |
bs-43522P |
英文名称 |
Recombinant human TGFBR2 protein, C-His (HEK293)
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中文名称 |
重组人转移生长因子β受体2蛋白 |
别 名 |
TGF-beta receptor type-2; TGF beta R2; TGFBR2; AAT 3; AAT3; FAA 3; FAA3; HNPCC6; MFS 2; MFS2; RIIC; TAAD 2; TAAD2; TbetaR II; TGF beta receptor type 2; TGF beta receptor type II; TGF beta type II receptor; TGFB R2; TGFbeta RII; TGFBR 2; TGFR 2; TGFR2; Transforming growth factor beta receptor II; Transforming growth factor beta receptor type II. ;Recombinant human TGFBR2 protein, C-His (HEK293) |
理论分子量 |
19.2 kDa |
检测分子量 |
23-38 |
性 状 |
Lyophilized or Liquid |
浓 度 |
>0.5 mg/ml |
物 种 |
Human |
序 列 |
23-159/567 |
纯 度 |
>90% as determined by SDS-PAGE |
纯化方法 |
AC |
内毒素 |
Not analyzed |
表达系统 |
HEK293 cell |
活性 |
Not tested |
标签 |
C-His |
缓 冲 液 |
PBS (pH7.4). |
保存条件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 |
This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.
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产品图片 |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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