| 产品编号 | bs-49194P |
| 英文名称 | Recombinant Chinese cobra Cytotoxin 1 protein, His |
| 中文名称 | 重组眼镜蛇蛇毒蛋白 |
| 别 名 | 3SA1_NAJAT; Cytotoxin 1 · Naja atra (Chinese cobra); Cytotoxin1; Recombinant Chinese cobra Cytotoxin 1 protein, His |
| 理论分子量 | 22.2kDa |
| 检测分子量 | 27 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | ＞0.5 mg/ml |
| 物 种 | Cobra |
| 序 列 | 22-81/81 |
| 纯 度 | >95% as determined by SDS-PAGE |
| 纯化方法 | AC |
| 内毒素 | Not analyzed |
| 表达系统 | E.coli |
| 活性 | Not tested |
| 标签 | His |
| 缓 冲 液 | 20mM Tris-HCl (pH8.0) with 0.25mM NaCl. |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
Basic protein that binds to cell membrane and depolarizes cardiomyocytes. It also shows lytic activities on many other cells, including red blood cells. Interaction with sulfatides in the cell membrane induces pore formation and cell internalization and is responsible for cytotoxicity in cardiomyocytes. It targets the mitochondrial membrane and induces mitochondrial swelling and fragmentation (By similarity).
It binds to the integrin alpha-V/beta-3 (ITGAV/ITGB3) with a moderate affinity and inhibits protein kinases C (PubMed:8448165).
It also binds with high affinity to heparin (PubMed:17685633). SWISS: P60304 Gene ID: N/A |
| 产品图片 |
The purity of the protein is greater than 51% as determined by reducing SDS-PAGE.
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
