| 产品编号 |
bs-43018P |
| 英文名称 |
Recombinant human Apolipoprotein E protein, C-His (HEK293)
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| 中文名称 |
重组人载脂蛋白E |
| 别 名 |
Apolipoprotein E precursor; AD2; Alzheimer disease 2; Apo E; ApoE; APOEA; ApolipoproteinE; Apolipoprotein-E; Apoprotein; MGC1571; Apo E2; ApoE2; APOE 2; Apolipoprotein E2; LDLCQ5; LPG; APOE_HUMAN; Apo-E; Recombinant human Apolipoprotein E protein, C-His (HEK293) |
| 克 隆 号 |
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| 理论分子量 |
38 kDa |
| 检测分子量 |
40 |
| 性 状 |
Lyophilized or Liquid |
| 浓 度 |
＞0.5 mg/ml |
| 物 种 |
Human |
| 序 列 |
19-317/317 |
| 纯 度 |
>95% as determined by SDS-PAGE |
| 纯化方法 |
AC |
| 内毒素 |
Not analyzed |
| 表达系统 |
HEK293 cell |
| 活性 |
Yes |
| 标签 |
C-His |
| 缓 冲 液 |
PBS (pH7.4). |
| 保存条件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. ApoE exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. Compared with E3 and E4, E2 exhibits the lowest receptor binding affinity. Defects in ApoE are a cause of hyperlipoproteinemia type III due to increased plasma cholesterol and triglycerides levels which are the consequence of impaired clearance of chylomicron and VLDL remnants.
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| 产品图片 |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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