| 产品编号 | bsm-51757M |
| 英文名称 | FGF4 Mouse mAb |
| 中文名称 | FGF4单克隆抗体 |
| 别 名 | Fibroblast Growth Factor4; Heparin Secretory Transforming Protein 1; Kaposi Sarcoma Oncogene; Fgf-4; Fgfk; Hstf-1; kFGF; KS3; MGC129266; MGC129267; HBGF-4; HST; HST-1; HSTF1; K-FGF; KS3; FGF4_HUMAN. |
| 研究领域 | 肿瘤 心血管 信号转导 生长因子和激素 |
| 抗体来源 | Mouse |
| 克隆类型 | Monoclonal |
| 克 隆 号 | M8F12 |
| 交叉反应 | Recombinant protein (predicted: Human,Mouse,Hamster) |
| 产品应用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 19 kDa |
| 检测分子量 | |
| 细胞定位 | 分泌型蛋白 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FGF4: 41-200/206 |
| 亚 型 | IgG1,Κ |
| 纯化方法 | affinity purified by Protein G |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. [provided by RefSeq]. Function: Can transform NIH 3T3 cells from a human stomach tumor (hst) and from karposi's sarcoma (KS3). It has a mitogenic activity. Subunit: Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors. Subcellular Location: Secreted. Similarity: Belongs to the heparin-binding growth factors family. SWISS: P08620 Gene ID: 2249 Database links: Entrez Gene: 2249 Human Entrez Gene: 14175 Mouse SwissProt: P08620 Human SwissProt: P11403 Mouse |
| 产品图片 |
Sample:
Lane 1: FGF4 recombinant protein
Primary: Anti-FGF4 (bsm-51757M) at 1/4000 dilution
Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution
Predicted band size: 19 kD
Observed band size: 22 kD
|
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
