| 产品编号 |
bsk11106 |
| 英文名称 |
Human Serpin E1/PAI-1 ELISA Kit
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| 中文名称 |
人纤溶酶原激活物抑制剂1酶联免疫试剂盒 |
| 别 名 |
SERPINE1, PAI, PAI-1, PAI1, PLANH1, serpin family E member 1 |
| 种 属 |
Human |
| 线性范围 |
0.312 - 20ng/mL |
| 应用范围 |
S/P/CC |
| 检测限 |
0.15ng/mL |
| 适用样品基质 |
cell culture supernates, serum, and plasma. |
| 保存条件 |
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.). |
| 注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
Plasminogen activator inhibitor-1 (PAI-1) also known as endothelial plasminogen activator inhibitor or serpin E1 is a protein that in humans is encoded by the SERPINE1 gene.PAI-1 is a serine protease inhibitor (serpin) that functions as the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), the activators of plasminogen and hence fibrinolysis (the physiological breakdown of blood clots). It is a serine protease inhibitor (serpin) protein (SERPINE1).The other PAI, plasminogen activator inhibitor-2 (PAI-2) is secreted by the placenta and only present in significant amounts during pregnancy. In addition, protease nexin acts as an inhibitor of tPA and urokinase. PAI-1, however, is the main inhibitor of the plasminogen activators.
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