产品编号 |
bsk11051 |
英文名称 |
Human DPPIV/CD26 ELISA Kit
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中文名称 |
人二肽酰多肽酶酶联免疫试剂盒 |
别 名 |
ADCP2; DPPIV; Dipeptidyl peptidase 4; ADABP; ADCP 2; Adenosine deaminase complexing protein 2; CD 26; CD26; CD26 antigen 3; Dipeptidyl peptidase 4; Dipeptidyl peptidase iv; Dipeptidylpeptidase 4; Dipeptidylpeptidase IV; DPP 4; DPP IV; DPP4; Intestinal dipeptidyl peptidase; T cell activation antigen CD26; TP 103; TP103. |
种 属 |
Human |
线性范围 |
31.25 - 2,000 pg/mL |
应用范围 |
S/P/CC |
检测限 |
7 pg/mL |
适用样品基质 |
cell culture supernates, serum, and plasma. |
保存条件 |
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.). |
注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 |
Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3.
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