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Mouse Anti-S100A2  antibody (bsm-51330M)
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说明书: 50ul  100ul  
50ul/1580.00元
100ul/2500.00元
大包装/询价
产品编号 bsm-51330M
英文名称 S100A2
中文名称 S100A2单克隆抗体
别    名 S100 calcium binding protein A2; CAN19; MGC111539; Protein S 100L; Protein S-100L; Protein S100 A2; Protein S100-A2; Protein S100L; S100 A2; S100 calcium-binding protein A2; S100A2; S100L; S10A2_HUMAN.  
研究领域 肿瘤  细胞生物  信号转导  细胞周期蛋白  结合蛋白  细胞分化  
抗体来源 Mouse
克隆类型 Monoclonal
克 隆 号 7G5
交叉反应 (predicted: Human)
产品应用 WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:20-50, ICC=1:20-50, IF=1:20-50
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 11kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human S100A2 
亚    型 IgG1
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The protein encoded by this gene is a member of the S100family of proteins containing 2 EF-hand calcium-binding motifs.S100 proteins are localized in the cytoplasm and/or nucleus of awide range of cells, and involved in the regulation of a number ofcellular processes such as cell cycle progression anddifferentiation. S100 genes include at least 13 members which arelocated as a cluster on chromosome 1q21. This protein may have atumor suppressor function. Chromosomal rearrangements and alteredexpression of this gene have been implicated in breast cancer.

Function:
May act as a modulator against excess calciumaccumulation in normal human mammary epithelial cells. May alsoplay a role in suppressing tumor cell growth.

Subunit:
Homodimer. Interacts with FKBP4.

Tissue Specificity:
A subset of epithelial cells including normalhuman mammary epithelial cells and keratinocytes.

Similarity:
Belongs to the S-100 family
Contains 2 EF-hand domains.

SWISS:
P29034

Gene ID:
6273

Database links:

Entrez Gene: 6273 Human

Entrez Gene: 628324 Mouse

Omim: 176993 Human

SwissProt: P29034 Human

Unigene: 516484 Human

Unigene: 489562 Mouse



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