| 产品编号 |
bs-41112P |
| 英文名称 |
Recombinant human Creatine Kinase B protein
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| 中文名称 |
重组人脑型肌酸激酶蛋白 |
| 别 名 |
B CK; B CK; B-CK; BB-CK; BCK; Brain creatine kinase; Ckb; CKBB; CK-BB; Creatine kinase B; Creatine kinase B chain; Creatine kinase B-type; Creatine Kinase BB Isoenzyme; Creatine Kinase BB Isoenzyme; Creatine Kinase BB Isoenzyme; Creatine kinase brain; Cre |
| 克 隆 号 |
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| 理论分子量 |
43 kDa |
| 检测分子量 |
50 |
| 性 状 |
Liquid |
| 浓 度 |
＞0.5 mg/ml |
| 物 种 |
Human |
| 序 列 |
1-381/381 |
| 纯 度 |
>90% as determined by SDS-PAGE |
| 纯化方法 |
AC |
| 内毒素 |
Not analyzed |
| 表达系统 |
E.coli |
| 活性 |
Not tested |
| 标签 |
N-His |
| 缓 冲 液 |
20mM Tris-HCl (pH8.0) with 150mM NaCl. |
| 保存条件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
The protein encoded by this gene, CK-BB, consists of a homodimer of two identical brain-type CK-B subunits. BB-CK is a cytoplasmic enzyme involved in cellular energy homeostasis, with certain fractions of the enzyme being bound to cell membranes, ATPases, and a variety of ATP-requiring enzymes in the cell. There, CK-BB forms tightly coupled microcompartments for in situ regeneration of ATP that has been used up. The encoded protein reversibly catalyzes the transfer of "energy-rich" phosphate between ATP and creatine or between phospho-creatine (PCr) and ADP. Its functional entity is a homodimer (CK-BB) in brain and smooth muscle as well as in other tissues and cells such as neuronal cells, retina, kidney, bone, etc. In heart, a heterodimer (CK-MB) shahil consisting of one CK-B brain-type CK subunit and one CK-M muscle-type CK subunit is prominently expressed. The encoded CK-BB and CK-MB proteins are members of the ATP:guanido phosphotransferase protein family.
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| 产品图片 |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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