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Mouse Anti-human CD34/FITC antibody (BF00601)
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25T/1580.00元
50T/2480.00元
100T/3680.00元
大包装/询价
产品编号 BF00601
英文名称 human CD34/FITC
中文名称 FITC标记小鼠抗人CD34单克隆抗体
别    名 CD34 antigen; CD34 molecule; Cluster designation 34; Hematopoietic progenitor cell antigen CD34; HPCA1; CD34_HUMAN.  
抗体来源 Mouse
克隆类型 Monoclonal
克 隆 号 4H11
交叉反应
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 39kDa
检测分子量 105-120
性    状 Liquid
免 疫 原 Recombinant human CD34 protein 
亚    型 Mouse IgG1
纯化方法 Affinity purified by Protein G
缓 冲 液 0.01M PBS, 0.5%BSA, 0.03% Proclin300
保存条件 Store at 2-8℃. Protect from light. Avoid freezing.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The highly glycosylated 75-120 kD antigen CD34 is possibly an adhesion molecule with a putative role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. It could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. CD34 is thought to have a role in presenting carbohydrate ligands to selectins. The intracellular chain of the CD34 antigen is a site of phosphorylation by activated protein kinase C, suggesting a putative role in signal transduction. Two isoforms of CD34 have been reported to be generated by alternative splicing. CD34 is highly expressed on hematopoietic progenitors, as well as on endothelial cells, brain, and testis. Staining for CD34 has been used to measure angiogenesis, which reportedly predicts tumor recurrence.

SWISS:
P28906

Gene ID:
947

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