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Mouse Anti-human CD8  antibody (bsm-30094M)
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说明书: 100ug  
100ug/1880.00元
大包装/询价

产品编号 bsm-30094M
英文名称 human CD8
中文名称 小鼠抗人CD8单克隆抗体
别    名 CD8 antigen, alpha polypeptide (p32); CD8a; CD8a antigen; CD8a molecule; CD8A_MOUSE; CD8A_HUMAN; Leu2; Leu2 T lymphocyte antigen; MAL; OKT8 T cell antigen; p32; T cell antigen Leu2; T cell co receptor; T-cell surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8/Leu-2; T8 T cell antigen.  
Specific References  (2)     |     bsm-30094M has been referenced in 2 publications.
[IF=9.918] Daijun Zhou. et al. An injectable miR181a-IFI6 nanoparticles promote high-quality healing of radiation-induced skin injury. MATER TODAY ADV. 2022 Aug;15:100267  FC ;  Human.  
[IF=9.776] Yingli Wang. et al. Paclitaxel derivative-based liposomal nanoplatform for potentiated chemo-immunotherapy. J Control Release. 2022 Jan;341:812  IF ;  Mouse.  
研究领域 细胞生物  免疫学  细胞表面分子  t-淋巴细胞  
抗体来源 Mouse
克隆类型 Monoclonal
克 隆 号 HIT8a
交叉反应 Human
产品应用 WB=1:500-2000, Flow-Cyt=1ug/Test
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 27kDa
检测分子量 32-34
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 Recombinant human CD8 
亚    型 Mouse IgG1, k
纯化方法 Affinity purified by Protein G
缓 冲 液 0.01M TBS(pH=7.4)
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020]

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Most prominently found in the gastrointestinal tract, skin, lung, and brain but not in liver.

Similarity:
Belongs to the PMP-22/EMP/MP20 family.

SWISS:
P01732

Gene ID:
925

Database links:

Entrez Gene: 925 Human

Entrez Gene: 926 Human

Entrez Gene: 12525 Mouse

Entrez Gene: 12526 Mouse

Omim: 186910 Human

SwissProt: P01732 Human

SwissProt: P10966 Human

SwissProt: P01731 Mouse

SwissProt: P10300 Mouse

Unigene: 405667 Human

Unigene: 85258 Human

Unigene: 1858 Mouse

Unigene: 333148 Mouse



产品图片
scatter diagram showing peripheral blood lymphocytes stained with CD8. The cells were incubated with the antibody (bsm-30094M) for 30 min at 22°C.The secondary antibody used for 40 min at room temperature. Acquisition of >10,000 events was performed.
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