| 产品编号 | bsm-30067M-PE |
| 英文名称 | human CD5/PE |
| 中文名称 | PE标记人CD5单克隆抗体 |
| 别 名 | T-cell surface glycoprotein CD5; Lymphocyte antigen 1; Ly-1; Lyt-1; CD5; CD5 antigen; CD 5; CD5 molecule; CD5 antigen (p56 62); CD5_HUMAN; LEU 1; LEU1; Ly12; LyA; Lymphocyte Antigen CD5; Lymphocyte antigen T1/Leu 1; Lymphocyte antigen T1/Leu-1; Lymphocyte glycoprotein T1/Leu1; OTTHUMP00000236973; p56 62; T1. PE anti-human CD5; |
| 研究领域 | 细胞生物 干细胞 细胞表面分子 |
| 抗体来源 | Mouse |
| 克隆类型 | Monoclonal |
| 克 隆 号 | HISM2 |
| 交叉反应 | |
| 产品应用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 55kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 亚 型 | IgG1 |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008] Function: May act as a receptor in regulating T-cell proliferation. Subunit: Interacts with CD72/LYB-2. Interacts with PTPN6/SHP-1. Subcellular Location: Cell membrane; Single-pass type I membrane protein. Post-translational modifications: Phosphorylated on tyrosine residues by LYN; this creates binding sites for PTPN6/SHP-1. Similarity: Contains 3 SRCR domains. SWISS: P06127 Gene ID: 921 Database links: Entrez Gene: 921 Human Omim: 153340 Human SwissProt: P06127 Human Unigene: 58685 Human |
| 产品图片 |
Flow cytometry staining of normal human peripheral blood cells with CD5/PE(bsm-30067M-PE)(Red histogram) or Mouse IgG1 Isotype Control (PE Conjugate)(C03-11002
)(Blue histogram) . Total cells were used for analysis.
|
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
