产品编号 |
bs-10859P |
英文名称 |
Recombinant human IL-1b protein, C-His
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中文名称 |
重组人白介素1β/IL-1β蛋白 |
别 名 |
Catabolin; H1; IL-1β; Hematopoietin 1; IFN beta inducing factor; IL 1; IL 1 beta; IL 1B; IL1B; IL1F2; Interleukin 1 beta; Interleukin 1 beta precursor; LAF; OAF; Osteoclast activating factor; Preinterleukin beta; Pro interleukin 1 beta; IL1B_HUMAN; Interl |
理论分子量 |
17 kDa |
检测分子量 |
17 |
性 状 |
Lyophilized or Liquid |
浓 度 |
>0.5 mg/ml |
物 种 |
Human |
序 列 |
117-269/269 |
纯 度 |
>95% as determined by SDS-PAGE |
纯化方法 |
AC |
内毒素 |
Not analyzed |
表达系统 |
E.coli |
活性 |
Not tested |
标签 |
C-His |
缓 冲 液 |
20mM Tris-HCl (pH7.5) with 8M Urea. |
保存条件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 |
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008].
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产品图片 |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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