| 产品编号 | bs-18210R |
| 英文名称 | Rabbit Anti-Calcitonin antibody |
| 中文名称 | 降钙素抗体 |
| 别 名 | Alpha CGRP; CALC 1; CALC A; CALC1; CALCA; Calcitonin related polypeptide alpha; CGRP 1; CGRP; CGRP I; CGRP-1; CGRPI; CGRP1; CT; Katacalcin; KC; MGC126648; alpha type CGRP; calcitonin 1; calcitonin gene related peptide 1; calcitonin gene related peptide I; calcitonin isoform CT preproprotein. |
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Specific References (2) | bs-18210R has been referenced in 2 publications.
[IF=4.132] Xiang, Chengyu. et al. Fasudil Ameliorates Osteoporosis Following Myocardial Infarction by Regulating Cardiac Calcitonin Secretion. J CARDIOVASC TRANSL. 2022 May;:1-14 IHC ; Mouse.
[IF=1.834] Fang Dai. et al. Effects of long term diabetogenic high fat diet on bone in ovariectomized female rats. BIOTECH HISTOCHEM. 2022 Jun 28 IHC ; Rat.
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| 研究领域 | 肿瘤 神经生物学 生长因子和激素 内分泌病 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse (predicted: Human,Rat,Rabbit,Dog,GuineaPig) |
| 产品应用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 细胞定位 | 分泌型蛋白 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Calcitonin: 85-116/141 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Calcitonin is a 32 amino acid peptide hormone synthesized by the parafollicular cells of the thyroid. It causes a rapid, but short lived, reduction in serum calcium and phosphate by promoting the incorporation of those ions in the bones. This effect is opposite to that of parathyroid hormone. Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors. Staining for calcitonin in medullary carcinoma of the thyroid produces a fine granular pattern in the cytoplasm. Amyloid deposits within the tumor may also exhibit varying degrees of calcitonin activity. Function: Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones. Katacalcin is a potent plasma calcium-lowering peptide Subcellular Location: Secreted. Similarity: Belongs to the calcitonin family. SWISS: P01258 Gene ID: 796 Database links: Entrez Gene: 796 Human Omim: 114130 Human SwissProt: P01258 Human Unigene: 37058 Human 降钙素(CT)是甲状腺滤泡旁细胞(C细胞)分泌的含有32个氨基酸的单链多肽，可使血钙、磷水平降低的一种多肽激素，脑组织和垂体含有降钙素，前列腺等其他组织也存在CT。主要用于C细胞增生和甲状腺髓样癌的诊断、也可用于其他类型的神经内分泌肿瘤的研究。 |
| 产品图片 |
Sample:
Cerebrum (Mouse) Lysate at 40 ug
Primary: Anti-Calcitonin (bs-18210R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 3.5/13 kD
Observed band size: 17 kD
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Calcitonin) Polyclonal Antibody, Unconjugated (bs-18210R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
