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Rabbit Anti-ARF4  antibody (bs-8750R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-8750R
英文名称 ARF4
中文名称 ADP核糖基化因子4抗体
别    名 ADP ribosylation factor 2; ADP ribosylation factor 4; ADP-ribosylation factor 4; ARF2; ARF4; ARF4_HUMAN.  
研究领域 细胞生物  信号转导  结合蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Chicken,Pig,Cow,Horse,Rabbit,Sheep)
产品应用 WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 20kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ARF4: 101-180/180 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene is a member of the human ARF gene family whose members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 5 ARF proteins and 11 ARF-like proteins and constitute one family of the RAS superfamily. The ARF proteins are categorized as class I, class II and class III; this gene is a class II member. The members of each class share a common gene organization. The ARF4 gene spans approximately 12kb and contains six exons and five introns. This gene is the most divergent member of the human ARFs. Conflicting map positions at 3p14 or 3p21 have been reported for this gene. [provided by RefSeq, Jul 2008]

Function:
GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.

Subcellular Location:
Golgi apparatus.

Similarity:
Belongs to the small GTPase superfamily. Arf family.

SWISS:
P18085

Gene ID:
378

Database links:

Entrez Gene: 769725 Chicken

Entrez Gene: 518601 Cow

Entrez Gene: 378 Human

Entrez Gene: 11843 Mouse

Entrez Gene: 595108 Pig

Entrez Gene: 79120 Rat

Omim: 601177 Human

SwissProt: Q3SZF2 Cow

SwissProt: P18085 Human

SwissProt: P61750 Mouse

SwissProt: P61751 Rat

Unigene: 652183 Human

Unigene: 297768 Mouse

Unigene: 35935 Rat



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