| 产品编号 | bs-20422R |
| 英文名称 | Neogenin |
| 中文名称 | 神经细胞粘附蛋白NGN抗体 |
| 别 名 | NGN; Neo1; Neo 1; Neogenin; NEO1_HUMAN. |
| 研究领域 | 细胞生物 神经生物学 细胞粘附分子 细胞分化 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human,Mouse,Rat,Dog,Cow,Sheep) |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 156kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Neogenin: 1001-1100/1461 <Extracellular> |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
This gene encodes a cell surface protein that is a memberof the immunoglobulin superfamily. The encoded protein consists offour N-terminal immunoglobulin-like domains, six fibronectin typeIII domains, a transmembrane domain and a C-terminal internaldomain that shares homology with the tumor suppressor candidategene DCC. This protein may be involved in cell growth anddifferentiation and in cell-cell adhesion. Defects in this gene areassociated with cell proliferation in certain cancers. Alternatesplicing results in multiple transcript variants. [provided byRefSeq, Feb 2010]. Function: Neogenin is one of several netrin-binding proteins. Neogenin functions as an Repulsive Guidance Molecule (RGM) receptor; RGM is implicated in axonal guidance and neural tube closure. Subunit: Interacts with RGMA. Interacts with MYO10 Subcellular Location: Cell membrane; Single-pass type I membraneprotein. Tissue Specificity: Widely expressed and also in cancer celllines. Similarity: Belongs to the immunoglobulin superfamily. DCC family. Contains 6 fibronectin type-III domains. Contains 4 Ig-like C2-type (immunoglobulin-like)domains. SWISS: Q92859 Gene ID: 4756 Database links: Entrez Gene: 4756 Human Entrez Gene: 18007 Mouse Omim: 601907 Human SwissProt: Q92859 Human SwissProt: P97798 Mouse Unigene: 388613 Human Unigene: 42249 Mouse Unigene: 10667 Rat |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
