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Rabbit Anti-PTPLA  antibody (bs-4428R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-4428R
英文名称 PTPLA
中文名称 蛋白酪氨酸磷酸酶PTPLA抗体
别    名 3-hydroxyacyl-CoA dehydratase 1; CAP; Cementum attachment protein; HACD1; HACD1_HUMAN; Protein-tyrosine phosphatase-like member A; PTPLA; RP23-334M9.1.  
研究领域 肿瘤  细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human)
产品应用 IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 32kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PTPLA: 1-100/288 <Cytoplasmic>
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The protein encoded by this gene contains a characteristic catalytic motif of the protein tyrosine phosphatases (PTPs) family. The PTP motif of this protein has the highly conserved arginine residue replaced by a proline residue; thus it may represent a distinct class of PTPs. Members of the PTP family are known to be signaling molecules that regulate a variety of cellular processes. This gene was preferentially expressed in both adult and fetal heart. A much lower expression level was detected in skeletal and smooth muscle tissues, and no expression was observed in other tissues. The tissue specific expression in the developing and adult heart suggests a role in regulating cardiac development and differentiation. [provided by RefSeq, Jul 2008]

Function:
Responsible for the dehydration step in very long-chain fatty acids (VLCFAs) synthesis.

Subcellular Location:
Endoplasmic reticulum membrane.

Tissue Specificity:
Highly expressed in the myocardium, and to a lesser extent in skeletal and smooth muscular tissues including those from stomach, jejunum, and bladder.

Similarity:
Belongs to the very long-chain fatty acids dehydratase HACD family.

SWISS:
B0YJ81

Gene ID:
9200

Database links:

Entrez Gene: 9200 Human

Entrez Gene: 30963 Mouse

Omim: 610467 Human

SwissProt: B0YJ81 Human

SwissProt: Q9QY80 Mouse

Unigene: 114062 Human



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