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Rabbit Anti-VPS37C  antibody (bs-12774R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-12774R
英文名称 VPS37C
中文名称 液泡蛋白分选蛋白37C抗体
别    名 5730409F24Rik; AU042646; ESCRT I complex subunit VPS37C; ESCRT-I complex subunit VPS37C; FLJ20847; hVps37C; PML39; RGD1309258; Vacuolar protein sorting 37 homolog C (S. cerevisiae); Vacuolar protein sorting 37C (yeast); Vacuolar protein sorting 37C; Vacuolar protein sorting associated protein 37C; Vacuolar protein sorting-associated protein 37C; VP37C_HUMAN; VPS37C.  
研究领域 细胞生物  信号转导  跨膜蛋白  细胞膜蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep)
产品应用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 39kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human VPS37C: 11-110/355 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 VPS37C is a subunit of ESCRT-I (endosomal sorting complex required for transport I), a complex in the class E vacuolar protein sorting (VPS) pathway required for sorting ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies (Eastman et al., 2005 [PubMed 15509564]).[supplied by OMIM, Mar 2008]

Function:
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.

Subcellular Location:
Late endosome membrane. Probably associates with membranes. Recruited to the plasma membrane by HIV-1.

Similarity:
Belongs to the VPS37 family.
Contains 1 VPS37 C-terminal domain.

SWISS:
A5D8V6

Gene ID:
55048

Database links:

Entrez Gene: 55048 Human

Entrez Gene: 107305 Mouse

Entrez Gene: 308178 Rat

Omim: 610038 Human

SwissProt: A5D8V6 Human

SwissProt: Q8R105 Mouse

Unigene: 523715 Human

Unigene: 19091 Mouse

Unigene: 12915 Rat



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