产品编号 | bs-12768R |
英文名称 | VPS26 Rabbit pAb |
中文名称 | 液泡蛋白分选蛋白26抗体 |
别 名 | FLJ12930; HB 58; HB58; Hbeta 58; Hbeta 58 homolog; Hbeta58; Hbeta58 homolog; hVPS 26; hVPS26; MGC94168; PEP 8A; PEP8A; Vacuolar protein sorting 26 A; Vacuolar protein sorting 26; Vacuolar protein sorting 26 homolog A; Vacuolar protein sorting 26 homolog A S. pombe; Vacuolar protein sorting 26 homolog A yeast; Vacuolar protein sorting 26 yeast; Vacuolar protein sorting 26 yeast homolog; Vacuolar protein sorting 26A; Vacuolar protein sorting associated protein 26A; Vacuolar protein sorting-associated protein 26A; Vesicle protein sorting 26; Vesicle protein sorting 26A; VP26A_HUMAN; VPS 26; VPS 26A; VPS26A. |
研究领域 | 细胞生物 信号转导 淋巴细胞 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human (predicted: Mouse,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Dog,Horse) |
产品应用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 38 kDa |
检测分子量 | |
细胞定位 | 细胞浆 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human VPS26: 21-120/327 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 |
This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] Function: Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Subcellular Location: Cytoplasm. Endosome membrane. Similarity: Belongs to the VPS26 family. SWISS: O75436 Gene ID: 9559 Database links: Entrez Gene: 9559 Human Entrez Gene: 30930 Mouse Omim: 605506 Human SwissProt: O75436 Human SwissProt: P40336 Mouse Unigene: 499925 Human Unigene: 260703 Mouse Unigene: 473468 Mouse Unigene: 3673 Rat |
产品图片 | |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |