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Rabbit Anti-PNPLA8  antibody (bs-12764R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-12764R
英文名称 PNPLA8
中文名称 磷脂酶patatin样域包含蛋白8抗体
别    名 Calcium-independent phospholipase A2-gamma; Intracellular membrane associated calcium independent phospholipase A2 gamma; Intracellular membrane-associated calcium-independent phospholipase A2 gamma; IPLA2 2; iPLA2 gamma; IPLA2(GAMMA); iPLA2-2; iPLA2-gamma; IPLA22; IPLA2G; Patatin like phospholipase domain containing protein 8; Patatin-like phospholipase domain-containing protein 8; PLPL8_HUMAN; PNPLA-gamma; PNPLA8.  
研究领域 肿瘤  心血管  细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: GuineaPig,Sheep,Rabbit,Horse,Cow,Pig,Dog,Rat,Mouse,Human)
产品应用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 88kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PNPLA8: 601-700/782 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a member of the patatin-like phospholipase domain containing protein family. Members of this family are phospholipases which catalyze the cleavage of fatty acids from membrane phospholipids. The product of this gene is a calcium-independent phospholipase. A pseudogene of this gene is located on the X chromosome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Function:
Calcium-independent phospholipase A2, which catalyzes the hydrolysis of the sn-2 position of glycerophospholipids, PtdSer and to a lower extent PtdCho. Cleaves membrane phospholipids.

Subcellular Location:
Endoplasmic reticulum membrane. Golgi apparatus membrane. Cytoplasm > perinuclear region.

Tissue Specificity:
Expressed in parenchymal tissues including heart, skeletal muscle, placenta, brain, liver and pancreas. Also expressed in bronchial epithelial cells and kidney. Highest expression is observed in skeletal muscle and heart.

Similarity:
Contains 1 patatin domain.

SWISS:
Q9NP80

Gene ID:
50604

Database links:

Entrez Gene: 50640 Human

Entrez Gene: 67452 Mouse

Entrez Gene: 314075 Rat

Omim: 612123 Human

SwissProt: Q9NP80 Human

SwissProt: Q8K1N1 Mouse

Unigene: 617340 Human

Unigene: 732217 Human

Unigene: 54126 Mouse

Unigene: 23073 Rat



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