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Rabbit Anti-PFAS  antibody (bs-12626R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-12626R
英文名称 PFAS
中文名称 甲酰甘氨酰胺核苷酸转移酶抗体
别    名 PFAS; FGAM synthase; FGAMS; FGAR amidotransferase; FGARAT; Formylglycinamide ribotide amidotransferase; Formylglycinamide ribotide synthetase; KIAA0361; Phosphoribosylformylglycinamidine synthase; PURL.  
研究领域 肿瘤  细胞生物  信号转导  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep)
产品应用 IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 145kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PFAS: 331-430/1338 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Purines are necessary for many cellular processes, including DNA replication, transcription, and energy metabolism. Ten enzymatic steps are required to synthesize inosine monophosphate (IMP) in the de novo pathway of purine biosynthesis. The enzyme encoded by this gene catalyzes the fourth step of IMP biosynthesis. [provided by RefSeq, Jul 2008]

Function:
Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate (By similarity).By similarity.

Subcellular Location:
Cytoplasmic

Similarity:
In the N-terminal section; belongs to the FGAMS family.
Contains 1 glutamine amidotransferase type-1 domain.

SWISS:
O15067

Gene ID:
5198

Database links:

Entrez Gene: 5198 Human

Entrez Gene: 237823 Mouse

Omim: 602133 Human

SwissProt: O15067 Human

SwissProt: Q5SUR0 Mouse

Unigene: 573976 Human

Unigene: 340288 Mouse



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