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Rabbit Anti-SLC6A15  antibody (bs-21024R)
~~~促销,代码KX240301~~~
~~~促销,代码KX240302~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-21024R
英文名称 SLC6A15
中文名称 碳酸氢钠协同转运蛋白6-A15抗体
别    名 hv7 3; MGC87066; NTT73; Orphan sodium and chloride dependent neurotransmitter transporter NTT73; Orphan transporter v7 3; S6A15_HUMAN; SBAT1; SLC6A15; sodium- and chloride-dependent neurotransmitter transporter NTT73; Sodium-coupled branched-chain amino-acid transporter 1; Sodium-dependent neutral amino acid transporter B(0)AT2; Solute carrier family 6 (neutral amino acid transporter) member 15; Solute carrier family 6 member 15; Transporter v7-3; V7 3.  
研究领域 肿瘤  细胞生物  神经生物学  信号转导  转运蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Chicken,Pig,Cow,Horse,Rabbit,Sheep)
产品应用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 82kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC6A15: 631-730/730 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a member of the solute carrier family 6 protein family which transports neutral amino acids. The encoded protein is thought to play a role in neuronal amino acid transport (PMID: 16185194) and may be associated with major depression (PMID: 21521612). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

Function:
Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for the branched-chain amino acids, particulary leucine, valine and isoleucine and methionine. Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1:1. May have a role as transporter for neurotransmitter precursors into neurons. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent.

Subcellular Location:
Membrane.

Tissue Specificity:
Almost exclusively expressed in the brain.

Similarity:
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
SLC6A15 subfamily.

SWISS:
Q9H2J7

Gene ID:
55117

Database links:

Entrez Gene: 55117 Human

Entrez Gene: 103098 Mouse

Entrez Gene: 282712 Rat

Omim: 607971 Human

SwissProt: Q9H2J7 Human

SwissProt: Q8BG16 Mouse

SwissProt: Q08469 Rat

Unigene: 44424 Human

Unigene: 458408 Mouse

Unigene: 9716 Rat



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