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PADI3 / PAD3 Rabbit pAb (bs-19621R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-19621R
英文名称 PADI3 / PAD3 Rabbit pAb
中文名称 蛋白质精氨酸亚型3抗体
别    名 PADI3_HUMAN; Protein-arginine deiminase type-3; EC:3.5.3.15; Peptidylarginine deiminase III; Protein-arginine deiminase type III; PDI3; UHS1;  
研究领域 细胞生物  免疫学  信号转导  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Horse)
产品应用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 75 kDa
检测分子量
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PADI3 / PAD3: 1-100/664 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type III enzyme modulates hair structural proteins, such as filaggrin in the hair follicle and trichohyalin in the inner root sheath, during hair follicle formation. Together with the type I enzyme, this enzyme may also play a role in terminal differentiation of the epidermis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008]

Function:
Catalyzes the deimination of arginine residues of proteins.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Hair follicles, and epidermis at very low levels.

Similarity:
Belongs to the protein arginine deiminase family.

SWISS:
Q9ULW8

Gene ID:
51702

Database links:

Entrez Gene: 51702 Human

Entrez Gene: 18601 Mouse

Entrez Gene: 29520 Rat

Omim: 606755 Human

SwissProt: Q9ULW8 Human

SwissProt: Q9Z184 Mouse

SwissProt: P70708 Rat

Unigene: 149195 Human

Unigene: 20851 Mouse

Unigene: 32094 Rat



产品图片
Sample: Pancreas (Mouse) Lysate at 40 ug Primary: Anti-PADI3 / PAD3 (bs-19621R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 75 kD Observed band size: 75 kD
Sample: Liver (Mouse) Lysate at 40 ug Primary: Anti-PADI3 / PAD3 (bs-19621R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 75 kD Observed band size: 75 kD
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