| 产品编号 | bs-19752R |
| 英文名称 | Rabbit Anti-SH3BP5 antibody |
| 中文名称 | SH3结构域结合蛋白5抗体 |
| 别 名 | 3BP5_HUMAN; OTTHUMP00000208289; OTTHUMP00000208291; OTTHUMP00000208294; SAB; SH3 binding protein; SH3 domain binding protein 5(BTK associated); SH3 domain binding protein 5; SH3 domain binding protein that preferentially associates with BTK; SH3 domain-binding protein 5; SH3 domain-binding protein that preferentially associates with BTK; SH3 domainbinding protein 5; SH3BP 5; SH3BP-5; Sh3bp5. |
| 研究领域 | 细胞生物 信号转导 细胞凋亡 激酶和磷酸酶 淋巴细胞 b-淋巴细胞 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human,Mouse (predicted: Rat,Rabbit,Pig,Cow,Zebrafish,Chicken,Dog,Horse) |
| 产品应用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 50 kDa |
| 检测分子量 | |
| 细胞定位 | 细胞浆 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SH3BP5: 1-100/455 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death. Subcellular Location: Mitochondrion. Tissue Specificity: Highly expressed in testis and ovaries. It is also expressed in a variety of tissues including spleen, lymph node, thymus, bone marrow, fetal liver, colon, small intestine and prostate. Similarity: Belongs to the SH3BP5 family. SWISS: Q7L8J4 Gene ID: 80851 Database links: Entrez Gene: 9467 Human Entrez Gene: 80851 Human Entrez Gene: 24056 Mouse Entrez Gene: 79566 Mouse Omim: 605612 Human SwissProt: O60239 Human SwissProt: Q7L8J4 Human SwissProt: Q99LH9 Mouse SwissProt: Q9Z131 Mouse Unigene: 11005 Cow Unigene: 257761 Human Unigene: 726063 Human Unigene: 290534 Mouse Unigene: 383198 Mouse Unigene: 163321 Rat |
| 产品图片 |
Sample:
Ovary (Mouse) Lysate at 40 ug
Testis (Mouse) Lysate at 40 ug
Jurkat (Human) Cell Lysate at 30 ug
Primary: Anti-SH3BP5 (bs-19752R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 50 kD
Observed band size: 50 kD
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
