| 产品编号 | bs-20061R |
| 英文名称 | phospho-FOXO6 (Ser184) |
| 中文名称 | 磷酸化叉头蛋白O6抗体 |
| 别 名 | Foxo6 (phospho Ser184); Foxo6 (phospho S184); Forkhead box protein O6; FOXO6_HUMAN. |
 |
Specific References (1) | bs-20061R has been referenced in 1 publications.
[IF=4.932] Yi Ren. et al. Pravastatin attenuates sepsis-induced acute lung injury through decreasing pulmonary microvascular permeability via inhibition of Cav-1/eNOS pathway. Int Immunopharmacol. 2021 Nov;100:108077 WB ; Mouse.
|
| 研究领域 | 细胞生物 转录调节因子 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human,Mouse,Rat,Cow,Horse,Sheep) |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 51kDa |
| 细胞定位 | 细胞核 细胞浆 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthesised phosphopeptide derived from human FOXO6 around the phosphorylation site of Ser184: AV(p-S)MD |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Murine Foxo6 is a member of the murine forkhead family of transcription factors. This family consists of over 30 members, the vast majority of which is important in embryonic development. These forkhead transcription factors may play a role in maintenance and survival of developing and adult neurons. Function: Transcriptional activator. Subcellular Location: Cytoplasmic and Nuclear. When phosphorylated, translocated from nucleus to cytoplasm. High nuclear localization after stimulation with growth factors. Post-translational modifications: Phosphorylation of Ser-184 is be important in regulating the transacriptional activity. Similarity: Contains 1 fork-head DNA-binding domain. SWISS: A8MYZ6 Gene ID: 100132074 Database links: Entrez Gene: 100132074 Human Entrez Gene: 329934 Mouse Omim: 611457 Human SwissProt: A8MYZ6 Human SwissProt: Q70KY4 Mouse Unigene: 277090 Mouse Unigene: 190858 Rat |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
