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LY6G6F Rabbit pAb (bs-20072R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-20072R
英文名称 LY6G6F Rabbit pAb
中文名称 淋巴细胞抗原6重复位点蛋白G6F抗体
别    名 C6orf21; Chromosome 6 open reading frame 21; G6F; G6f protein [Precursor]; HCG43720, isoform CRA_c; LY66F_HUMAN; LY6G6D; Ly6g6f; Lymphocyte antigen 6 complex locus G6F; Lymphocyte antigen 6 complex locus protein G6f; Lymphocyte antigen 6 complex, locus G6D; NG32.  
研究领域 细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 (predicted: Human)
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 32 kDa
检测分子量
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LY6G6F: 101-200/279 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 lymphocyte antigen 6 complex locus protein G6f is a single-pass type I membrane protein belonging to the immunoglobulin (Ig) superfamily. Located in the class III region of the major histocompatibility complex (MHC), the G6f gene lies in a cluster of genes encoding cell-surface proteins that play a role in the immune system and cellular recognition. G6f functions as a downstream effector of GRB2 and GRB7, and, in humans, it interacts with GRB2 and GRB7 through the phosphorylation of a tyrosine residue (Tyr 281) in the intracellular tail of G6f. This interaction is also mediated by the SH2 domain of GRB2 and possibly that of GRB7. G6f is a 297 amino acid protein, and it forms a disulfide-linked homodimer.

Function:
May play a role in the downstream signal transduction pathways involving GRB2 and GRB7.

Subcellular Location:
Cell membrane.

Post-translational modifications:
modificationsN-glycosylated.

Similarity:
Contains 1 Ig-like V-type (immunoglobulin-like) domain.

SWISS:
Q7Z5H2

Gene ID:
259215

Database links:

Entrez Gene: 259215 Human

Omim: 611404 Human

SwissProt: Q5SQ64 Human

SwissProt: Q7Z5H2 Human

Unigene: 591794 Human



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