| 产品编号 | bs-19282R |
| 英文名称 | NLRC3 |
| 中文名称 | 凋亡加强结构域蛋白15样蛋白抗体 |
| 别 名 | CARD15-like; CARD15-like protein; Caterpiller 16.2; Caterpiller protein 16.2; CLR16.2; FLJ00348; NLR family, CARD domain containing 3; Nlrc3; NLRC3_HUMAN; NOD-like receptor C3; NOD3; NOD3 protein; Nucleotide-binding oligomerization domain protein 3; Nucleotide-binding oligomerization domain protein 3 caterpiller 16.2; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 3; Protein NLRC3. |
| 研究领域 | 细胞生物 结合蛋白 淋巴细胞 t-淋巴细胞 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human (predicted: Sheep,Cow,Pig,Mouse) |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 115kDa |
| 细胞定位 | 细胞浆 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NLRC3: 721-820/1065 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
This gene encodes a NOD-like receptor family member. The encoded protein is a cytosolic regulator of innate immunity. This protein directly interacts with stimulator of interferon genes (STING), to prevent its proper trafficking, resulting in disruption of STING-dependent activation of the innate immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] Function: May modulate T-cell activation. Decreases the transcription of genes that are normally up-regulated after T-cell stimulation. Delays degradation of NFKBIA/IKBA. Subcellular Location: Cytoplasm. Tissue Specificity: Detected in peripheral blood mononuclear cells. Similarity: Belongs to the NLRP family. Contains 16 LRR (leucine-rich) repeats. Contains 1 NACHT domain. SWISS: Q7RTR2 Gene ID: 197358 Database links: Entrez Gene: 197358 Human Entrez Gene: 268857 Mouse SwissProt: Q7RTR2 Human SwissProt: Q5DU56 Mouse Unigene: 2061102 Human Unigene: 728268 Human Unigene: 215994 Mouse |
| 产品图片 |
Sample:
Lane 1: Human RAMOS cell lysates Lane 2: Human MCF-7 cell lysates Lane 3: Human SH-SY5Y cell lysates Lane 4: Human Jurkat cell lysates Primary: Anti-NLRC3 (bs-19282R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 115 kDa Observed band size: 120 kDa |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
