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NELL1 Rabbit pAb (bs-10704R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-10704R
英文名称 NELL1 Rabbit pAb
中文名称 蛋白激酶C结合蛋白NELL1抗体
别    名 IDH3GL; NEL like protein 1; Nel related protein 1; NEL-like protein 1; Nel-related protein 1; Nell1; NELL1_HUMAN; Neural epidermal growth factor like 1; NRP1; Protein kinase C binding protein NELL1; Protein kinase C-binding protein NELL1.  
研究领域 细胞生物  神经生物学  信号转导  生长因子和激素  激酶和磷酸酶  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Mouse (predicted: Human,Rat,Rabbit,Sheep,Cow)
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 87 kDa
检测分子量
细胞定位 分泌型蛋白 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NELL1: 201-300/810 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a cytoplasmic protein that contains epidermal growth factor (EGF)-like repeats. The encoded heterotrimeric protein may be involved in cell growth regulation and differentiation. A similar protein in rodents is involved in craniosynostosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

Function:
Involved in the control of cell growth and differentiation.

Subunit:
Homotrimer. Binds to PKC beta-1. Interacts with ATRAID; the interaction promotes osteoblast cell differentiation and mineralization.

Subcellular Location:
Secreted.

Similarity:
Contains 6 EGF-like domains.
Contains 1 TSP N-terminal (TSPN) domain.
Contains 5 VWFC domains.

SWISS:
Q92832

Gene ID:
4745

Database links:

Entrez Gene: 4745 Human

Entrez Gene: 338352 Mouse

Entrez Gene: 81733 Rat

Omim: 602319 Human

SwissProt: Q92832 Human

SwissProt: Q2VWQ2 Mouse

SwissProt: Q62919 Rat

Unigene: 657172 Human

Unigene: 383528 Mouse

Unigene: 10695 Rat



产品图片
Paraformaldehyde-fixed, paraffin embedded (mouse cerebellum); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (NELL1) Polyclonal Antibody, Unconjugated (bs-10704R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (NELL1) Polyclonal Antibody, Unconjugated (bs-10704R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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