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RPS7 Rabbit pAb (bs-18833R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
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产品编号 bs-18833R
英文名称 RPS7 Rabbit pAb
中文名称 核糖体蛋白S7抗体
别    名 40S ribosomal protein S7; DBA8; Ribosomal protein S7; RPS 7; rps7; RS7_HUMAN; S7.  
研究领域 细胞生物  免疫学  信号转导  转录调节因子  激酶和磷酸酶  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Mouse,Rat (predicted: Human,Sheep,Cow,Zebrafish)
产品应用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 22 kDa
检测分子量
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RPS7: 1-100/194 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S7E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Function:
Required for rRNA maturation.

DISEASE:
Defects in RPS7 are the cause of Diamond-Blackfan anemia type 8 (DBA8) [MIM:612563]. DBA8 is a form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies.

Similarity:
Belongs to the ribosomal protein S7e family.

SWISS:
P62081

Gene ID:
6201

Database links:

Entrez Gene: 505507 Cow

Entrez Gene: 6201 Human

Entrez Gene: 20115 Mouse

Entrez Gene: 29258 Rat

Entrez Gene: 393725 Zebrafish

Omim: 603658 Human

SwissProt: A6H769 Cow

SwissProt: P62081 Human

SwissProt: P62082 Mouse

SwissProt: P62083 Rat

SwissProt: P62084 Zebrafish

Unigene: 7187 Cow

Unigene: 534346 Human

Unigene: 546287 Human

Unigene: 646582 Human

Unigene: 279839 Mouse

Unigene: 371579 Mouse

Unigene: 107039 Rat

Unigene: 224475 Rat

Unigene: 28230 Zebrafish



产品图片
Sample: Lymph node (Mouse) Lysate at 40 ug Primary: Anti-RPS7 (bs-18833R) at 1/500 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 22 kD Observed band size: 22 kD
Paraformaldehyde-fixed, paraffin embedded (rat brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (RPS7) Polyclonal Antibody, Unconjugated (bs-18833R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (RPS7) Polyclonal Antibody, Unconjugated (bs-18833R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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